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Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy
Many antidepressants are cationic amphipaths, which spontaneously accumulate in natural or reconstituted membranes in the absence of their specific protein targets. However, the clinical relevance of cellular membrane accumulation by antidepressants in the human brain is unknown and hotly debated. H...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329523/ https://ncbi.nlm.nih.gov/pubmed/22529904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034024 |
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