Biodegradable Thermosensitive Hydrogel for SAHA and DDP Delivery: Therapeutic Effects on Oral Squamous Cell Carcinoma Xenografts

BACKGROUND: OSCC is one of the most common malignancies and numerous clinical agents currently applied in combinative chemotherapy. Here we reported a novel therapeutic strategy, SAHA and DDP-loaded PECE (SAHA-DDP/PECE), can improve the therapeutic effects of intratumorally chemotherapy on OSCC cell...

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Autores principales: Li, Jing, Gong, Changyang, Feng, Xiaodong, Zhou, Xikun, Xu, Xiaoping, Xie, Liang, Wang, Ruinan, Zhang, Dunfang, Wang, Hui, Deng, Peng, Zhou, Min, Ji, Ning, Zhou, Yu, Wang, Yun, Wang, Zhiyong, Liao, Ga, Geng, Ning, Chu, Liangyin, Qian, Zhiyong, Wang, Zhi, Chen, Qianming
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329521/
https://ncbi.nlm.nih.gov/pubmed/22529899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033860
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