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Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells

Elucidating mechanisms of cell cycle control in normally quiescent human pancreatic β-cells has the potential to impact regeneration strategies for diabetes. Previously we demonstrated that Id3, a repressor of basic Helix-Loop-Helix (bHLH) proteins, was sufficient to induce cell cycle entry in pancr...

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Detalhes bibliográficos
Main Authors: Lee, Seung-Hee, Hao, Ergeng, Levine, Fred, Itkin-Ansari, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329516/
https://ncbi.nlm.nih.gov/pubmed/21964314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.3.6.17923
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