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Mathematical modeling demonstrates how multiple slow processes can provide adjustable control of islet bursting
Pancreatic islets exhibit bursting oscillations that give rise to oscillatory Ca(2+) entry and insulin secretion from β-cells. These oscillations are driven by a slowly activating K(+) current, K(slow), which is composed of two components: an ATP-sensitive K(+) current and a Ca(2+)-activated K(+) cu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329513/ https://ncbi.nlm.nih.gov/pubmed/21934356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.3.6.17636 |
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