The p250GAP Gene Is Associated with Risk for Schizophrenia and Schizotypal Personality Traits

BACKGROUND: Hypofunction of the glutamate N-Methyl-d-aspartate (NMDA) receptor has been implicated in the pathophysiology of schizophrenia. p250GAP is a brain-enriched NMDA receptor-interacting RhoGAP. p250GAP is involved in spine morphology, and spine morphology has been shown to be altered in the...

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Autori principali: Ohi, Kazutaka, Hashimoto, Ryota, Nakazawa, Takanobu, Okada, Takeya, Yasuda, Yuka, Yamamori, Hidenaga, Fukumoto, Motoyuki, Umeda-Yano, Satomi, Iwase, Masao, Kazui, Hiroaki, Yamamoto, Tadashi, Kano, Masanobu, Takeda, Masatoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329470/
https://ncbi.nlm.nih.gov/pubmed/22530067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035696
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