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9G4 Autoreactivity Is Increased in HIV-Infected Patients and Correlates with HIV Broadly Neutralizing Serum Activity

The induction of a broadly neutralizing antibody (BNAb) response against HIV-1 would be a desirable feature of a protective vaccine. Vaccine strategies thus far have failed to elicit broadly neutralizing antibody responses; however a minority of HIV-infected patients do develop circulating BNAbs, fr...

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Detalhes bibliográficos
Main Authors: Kobie, James J., Alcena, Danielle C., Zheng, Bo, Bryk, Peter, Mattiacio, Jonelle L., Brewer, Matthew, LaBranche, Celia, Young, Faith M., Dewhurst, Stephen, Montefiori, David C., Rosenberg, Alexander F., Feng, Changyong, Jin, Xia, Keefer, Michael C., Sanz, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329433/
https://ncbi.nlm.nih.gov/pubmed/22530008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035356
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