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Nuclear Reprogramming: Kinetics of Cell Cycle and Metabolic Progression as Determinants of Success

Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage. Inadequate adaptation of the somatic nucleus to the embryonic cell cy...

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Autors principals: Balbach, Sebastian Thomas, Esteves, Telma Cristina, Houghton, Franchesca Dawn, Siatkowski, Marcin, Pfeiffer, Martin Johannes, Tsurumi, Chizuko, Kanzler, Benoit, Fuellen, Georg, Boiani, Michele
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329427/
https://ncbi.nlm.nih.gov/pubmed/22530006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035322
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