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Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression

Although statin therapy is a cornerstone of current low density lipoprotein (LDL)-lowering strategies, there is a need for additional therapies to incrementally lower plasma LDL cholesterol. In this study, we investigated the effect of several methylenedioxyphenol derivatives in regulating LDL chole...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ying, Zhekang, Desikan, Rajagopal, Xu, Xiaohua, Maiseyeu, Andrei, Liu, Cuiqing, Sun, Qinghua, Ziouzenkova, Ouiliana, Parthasarathy, Sampath, Rajagopalan, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329387/
https://ncbi.nlm.nih.gov/pubmed/22355094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M022806
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