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The Effects of Thrombin on Adenyl Cyclase Activity and a Membrane Protein from Human Platelets

Washed human platelets were incubated with 0.1-1.0 U/ml human thrombin and the effects on adenyl cyclase activity and on a platelet membrane protein (designated thrombin-sensitive protein) were studied. Adenyl cyclase activity was decreased 70-90% when intact platelets were incubated with thrombin....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Brodie, G. N., Baenziger, Nancy Lewis, Chase, Lewis R., Majerus, Philip W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1972
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4331802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106800
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