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IL-1RI (interleukin-1 receptor type I) signalling is essential for host defence and hemichannel activity during acute central nervous system bacterial infection

Staphylococcus aureus is a common aetiological agent of bacterial brain abscesses. We have previously established that a considerable IL-1 (interleukin-1) response is elicited immediately following S. aureus infection, where the cytokine can exert pleiotropic effects on glial activation and blood–br...

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Bibliografische gegevens
Hoofdauteurs: Xiong, Juan, Burkovetskaya, Maria, Karpuk, Nikolay, Kielian, Tammy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Neurochemistry 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328864/
https://ncbi.nlm.nih.gov/pubmed/22414156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20120008
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