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Wakefulness Affects Synaptic and Network Activity by Increasing Extracellular Astrocyte-Derived Adenosine

Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is rapidly converted to adenosine in the extracellula...

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Detalhes bibliográficos
Main Authors: Schmitt, L. Ian, Sims, Robert E., Dale, Nicholas, Haydon, Philip G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328785/
https://ncbi.nlm.nih.gov/pubmed/22457491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5689-11.2012
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