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Anisotropy of the Coulomb Interaction between Folded Proteins: Consequences for Mesoscopic Aggregation of Lysozyme

Toward quantitative description of protein aggregation, we develop a computationally efficient method to evaluate the potential of mean force between two folded protein molecules that allows for complete sampling of their mutual orientation. Our model is valid at moderate ionic strengths and account...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chan, Ho Yin, Lankevich, Vladimir, Vekilov, Peter G., Lubchenko, Vassiliy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328725/
https://ncbi.nlm.nih.gov/pubmed/22768950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.025
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