Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: Engagement of CD33 induces apoptosis of leukemic cells

p75/AIRM-1 is a recently identified inhibitory receptor expressed by natural killer and myeloid cells displaying high homology with CD33. Crosslinking of p75/AIRM-1 or CD33 has been shown to sharply inhibit the in vitro proliferation of both normal myeloid cells and chronic myeloid leukemias. In thi...

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Main Authors: Vitale, Chiara, Romagnani, Chiara, Puccetti, Antonio, Olive, Daniel, Costello, Regis, Chiossone, Laura, Pitto, Anna, Bacigalupo, Andrea, Moretta, Lorenzo, Mingari, Maria Cristina
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2001
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC33287/
https://ncbi.nlm.nih.gov/pubmed/11320212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091097198
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