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Spatiotemporal cGMP Dynamics in Living Mouse Rods

Signaling of single photons in rod photoreceptors decreases the concentration of the second messenger, cyclic GMP (cGMP), causing closure of cGMP-sensitive channels located in the plasma membrane. Whether the spatiotemporal profiles of the fall in cGMP are narrow and deep, or broad and shallow, has...

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Détails bibliographiques
Auteurs principaux: Gross, Owen P., Pugh, Edward N., Burns, Marie E.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328695/
https://ncbi.nlm.nih.gov/pubmed/22768933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.035
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