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Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy

The efficacy of photodynamic therapy (PDT) depends upon the delivery of both photosensitizing drug and oxygen. In this study, we hypothesized that local vascular microenvironment is a determinant of tumor response to PDT. Tumor vascularization and its basement membrane (collagen) were studied as a f...

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Библиографические подробности
Главные авторы: Maas, Amanda L., Carter, Shirron L., Wileyto, E. Paul, Miller, Joann, Yuan, Min, Yu, Guoqiang, Durham, Amy C., Busch, Theresa M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328659/
https://ncbi.nlm.nih.gov/pubmed/22374982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3744
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