Tumor progression-related transmembrane protein aspartate β-hydroxylase is a target for immunotherapy of hepatocellular carcinoma

BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) has a poor survival rate due to recurrent intrahepatic metastases and lack of effective adjuvant therapy. Aspartate-β-hydroxylase (ASPH) is an attractive cellular target since it is a highly conserved transmembrane protein overexpressed on both murine...

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Main Authors: Shimoda, Masafumi, Tomimaru, Yoshito, Charpentier, Kevin P., Safran, Howard, Carlson, Rolf I., Wands, Jack
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328647/
https://ncbi.nlm.nih.gov/pubmed/22245894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2011.12.016
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