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A Role for the Warburg Effect in Preimplantation Embryo Development: Metabolic Modification to Support Rapid Cell Proliferation

In this essay, we propose that embryos express a metabolic phenotype necessarily different from that of differentiated somatic cells and more like that of rapidly proliferating cancer cells. This metabolic adaptation, known as the Warburg Effect, supports rapid cell proliferation. One of the hallmar...

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Detalhes bibliográficos
Main Authors: Krisher, Rebecca L., Prather, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328638/
https://ncbi.nlm.nih.gov/pubmed/22431437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.22037
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