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Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms

Infection with Neisseria gonorrhoeae does not induce specific immunity or immune memory. Our previous studies in a murine model of vaginal gonococcal infection showed that innate immunity governed by Th17 cells was a critical aspect of the immune response elicited by this pathogen. Herein we show th...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Yingru, Islam, Epshita A., Jarvis, Gary A., Gray-Owen, Scott D., Russell, Michael W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328619/
https://ncbi.nlm.nih.gov/pubmed/22354319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.12
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