Common Variation at BARD1 Results in the Expression of an Oncogenic Isoform that Influences Neuroblastoma Susceptibility and Oncogenicity

The mechanisms underlying genetic susceptibility at loci discovered by genome-wide association study (GWAS) approaches in human cancer remain largely undefined. In this study we characterized the high-risk neuroblastoma association at the BRCA1-related locus, BARD1, showing that disease-associated v...

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Detalhes bibliográficos
Main Authors: Bosse, Kristopher R., Diskin, Sharon J., Cole, Kristina A., Wood, Andrew C., Schnepp, Robert W., Norris, Geoffrey, Nguyen, Le B., Jagannathan, Jayanti, Laquaglia, Michael, Winter, Cynthia, Diamond, Maura, Hou, Cuiping, Attiyeh, Edward F., Mosse, Yael P., Pineros, Vanessa, Dizin, Eva, Zhang, Yongqiang, Asgharzadeh, Shahab, Seeger, Robert C., Capasso, Mario, Pawel, Bruce R., Devoto, Marcella, Hakonarson, Hakon, Rappaport, Eric F., Irminger-Finger, Irmgard, Maris, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328617/
https://ncbi.nlm.nih.gov/pubmed/22350409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3703
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