Early Treatment With Olmesartan Prevents Juxtamedullary Glomerular Podocyte Injury and the Onset of Microalbuminuria in Type 2 Diabetic Rats

BACKGROUND: Studies were performed to determine if early treatment with an angiotensin II (Ang II) receptor blocker (ARB), olmesartan, prevents the onset of microalbuminuria by attenuating glomerular podocyte injury in Otsuka Long-Evans Tokushima Fatty (OLETF) rats with type 2 diabetes mellitus. MET...

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Main Authors: Sofue, Tadashi, Kiyomoto, Hideyasu, Kobori, Hiroyuki, Urushihara, Maki, Nishijima, Yoko, Kaifu, Kumiko, Hara, Taiga, Matsumoto, Sachiko, Ichimura, Atsuhiko, Ohsaki, Hiroyuki, Hitomi, Hirofumi, Kawachi, Hiroshi, Hayden, Melvin R., Whaley-Connell, Adam, Sowers, James R., Ito, Sadayoshi, Kohno, Masakazu, Nishiyama, Akira
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Kidney
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328599/
https://ncbi.nlm.nih.gov/pubmed/22318512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2012.1
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