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Polysaccharide Specific Monoclonal Antibodies Provide Passive Protection against Intranasal Challenge with Burkholderia pseudomallei

Burkholderia pseudomallei is a Gram-negative bacillus that is the causative agent of melioidosis. The bacterium is inherently resistant to many antibiotics and mortality rates remain high in endemic areas. The lipopolysaccharide (LPS) and capsular polysaccharide (CPS) are two surface-associated anti...

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Autors principals: AuCoin, David P., Reed, Dana E., Marlenee, Nicole L., Bowen, Richard A., Thorkildson, Peter, Judy, Barbara M., Torres, Alfredo G., Kozel, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328442/
https://ncbi.nlm.nih.gov/pubmed/22530013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035386
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