The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration

The Arp2/3 complex nucleates the formation of the dendritic actin network at the leading edge of motile cells, but it is still unclear if the Arp2/3 complex plays a critical role in lamellipodia protrusion and cell motility. Here, we differentiated motile fibroblast cells from isogenic mouse embryon...

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Bibliographic Details
Main Authors: Suraneni, Praveen, Rubinstein, Boris, Unruh, Jay R., Durnin, Michael, Hanein, Dorit, Li, Rong
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328382/
https://ncbi.nlm.nih.gov/pubmed/22492726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112113
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