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The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

The Mst1 kinase is an important regulator of murine T cell adhesion, migration, proliferation, and apoptosis. In this study, we analyze mice lacking both Mst1 and Mst2 in hematopoietic cells. Compared with wild-type mice, these double knockout (DKO) mice exhibit a severe reduction in the number of m...

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Detalhes bibliográficos
Main Authors: Mou, Fan, Praskova, Maria, Xia, Fan, Van Buren, Denille, Hock, Hanno, Avruch, Joseph, Zhou, Dawang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328371/
https://ncbi.nlm.nih.gov/pubmed/22412158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111692
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