Transglutaminase is essential for IgA nephropathy development acting through IgA receptors

IgA nephropathy (IgAN) is a common cause of renal failure worldwide. Treatment is limited because of a complex pathogenesis, including unknown factors favoring IgA1 deposition in the glomerular mesangium. IgA receptor abnormalities are implicated, including circulating IgA–soluble CD89 (sCD89) compl...

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Autori principali: Berthelot, Laureline, Papista, Christina, Maciel, Thiago T., Biarnes-Pelicot, Martine, Tissandie, Emilie, Wang, Pamela H.M., Tamouza, Houda, Jamin, Agnès, Bex-Coudrat, Julie, Gestin, Aurelie, Boumediene, Ahmed, Arcos-Fajardo, Michelle, England, Patrick, Pillebout, Evangéline, Walker, Francine, Daugas, Eric, Vrtosvnik, François, Flamant, Martin, Benhamou, Marc, Cogné, Michel, Moura, Ivan C., Monteiro, Renato C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328362/
https://ncbi.nlm.nih.gov/pubmed/22451718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112005
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