Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

Effective antiviral immunity depends on the ability of infected cells or cells triggered with virus-derived nucleic acids to produce type I interferon (IFN), which activates transcription of numerous antiviral genes. However, disproportionately strong or chronic IFN expression is a common cause of i...

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Hlavní autoři: Fang, Terry C., Schaefer, Uwe, Mecklenbrauker, Ingrid, Stienen, Astrid, Dewell, Scott, Chen, Marie S., Rioja, Inmaculada, Parravicini, Valentino, Prinjha, Rab K., Chandwani, Rohit, MacDonald, Margaret R., Lee, Kevin, Rice, Charles M., Tarakhovsky, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328357/
https://ncbi.nlm.nih.gov/pubmed/22412156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112343
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