Prenatal NMDA Receptor Antagonism Impaired Proliferation of Neuronal Progenitor, Leading to Fewer Glutamatergic Neurons in the Prefrontal Cortex

N-methyl--aspartate (NMDA) receptor is a glutamate receptor which has an important role on mammalian brain development. We have reported that prenatal treatment with phencyclidine (PCP), a NMDA receptor antagonist, induces long-lasting behavioral deficits and neurochemical changes. However, the mech...

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Bibliographische Detailangaben
Hauptverfasser: Toriumi, Kazuya, Mouri, Akihiro, Narusawa, Shiho, Aoyama, Yuki, Ikawa, Natsumi, Lu, Lingling, Nagai, Taku, Mamiya, Takayoshi, Kim, Hyoung-Chun, Nabeshima, Toshitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327844/
https://ncbi.nlm.nih.gov/pubmed/22257896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.324
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