Down-regulation of the serotonin transporter in hyperreactive platelets counteracts the pro-thrombotic effect of serotonin

An elevated plasma concentration of serotonin ([5-HT]) is a common feature of cardiovascular disease often associated with enhanced platelet activation and thrombosis. Whether elevated in vivo plasma 5-HT per se represents an independent risk factor for platelet hyperreactivity or only is an epiphen...

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Bibliographic Details
Main Authors: Ziu, Endrit, Mercado, Charles P., Li, Yicong, Singh, Preeti, Ahmed, Billow A., Freyaldenhoven, Samuel, Lensing, Shelly, Ware, Jerry, Kilic, Fusun
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327821/
https://ncbi.nlm.nih.gov/pubmed/22366712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.02.004
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