Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5

Glucocorticoids may play a significant role in the etiology of neuropsychiatric illnesses. Abnormalities in plasma cortisol levels, glucocorticoid sensitivity, and HPA-axis function often accompany clinical symptoms of stress-related illnesses such as PTSD and depression. Of particular interest are...

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Main Authors: Yang, Xiaoju, Ewald, Erin R., Huo, Yuqing, Tamashiro, Kellie L., Salvatori, Roberto, Sawa, Akira, Wand, Gary S., Lee, Richard S.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327767/
https://ncbi.nlm.nih.gov/pubmed/22445894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.03.035
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