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Cosmid walking and chromosome jumping in the region of PKD1 reveal a locus duplication and three CpG islands.
The locus responsible for the most common form of autosomal dominant polycystic kidney disease (PKD1) is located on chromosome 16p13.3. Genetic mapping studies indicate that PKD1 is flanked on the proximal side by the DNA marker 26.6 (D16S125). Here we show that 26.6 has undergone a locus duplicatio...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
1990
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC332771/ https://ncbi.nlm.nih.gov/pubmed/1979857 |
| Etykiety: |
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