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Plus-end Directed Myosins Accelerate Actin Filament Sliding by Single-headed Myosin VI

Myosin VI (Myo6) is unique among myosins in that it moves toward the minus (pointed) end of the actin filament. Thus to exert tension on, or move cargo along an actin filament, Myo6 is working against potentially multiple plus (barbed)-end myosins. To test the effect of plus-end motors on Myo6, the...

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Bibliographic Details
Main Authors: Ramamurthy, Bhagavathi, Cao, Wenxiang, De La Cruz, Enrique M., Mooseker, Mark S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327287/
https://ncbi.nlm.nih.gov/pubmed/22213699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21002
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