High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer

BACKGROUND: Lin28 is a negative regulator of the tumour suppressor microRNA, let-7, suggesting its role in tumourigenesis. However, the clinical significance of Lin28 expression in oesophageal cancer has not been elucidated. METHODS: Lin28 and Lin28B expression was examined by immunohistochemistry i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hamano, R, Miyata, H, Yamasaki, M, Sugimura, K, Tanaka, K, Kurokawa, Y, Nakajima, K, Takiguchi, S, Fujiwara, Y, Mori, M, Doki, Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326671/
https://ncbi.nlm.nih.gov/pubmed/22433967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.90
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