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Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor
The androgen receptor (AR) is known to play a critical role in prostate cancer (PC). p53 likely also plays a role given that p53 mutations are commonly found in advanced PC, and loss of wild-type protein function contributes to the phenotype of castration-resistant prostate cancer (CRPC). Neverthele...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Impact Journals LLC
2012
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326648/ https://ncbi.nlm.nih.gov/pubmed/22383394 |
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