Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor

The androgen receptor (AR) is known to play a critical role in prostate cancer (PC). p53 likely also plays a role given that p53 mutations are commonly found in advanced PC, and loss of wild-type protein function contributes to the phenotype of castration-resistant prostate cancer (CRPC). Neverthele...

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Detalhes bibliográficos
Main Authors: Guseva, Natalya V., Rokhlin, Oskar W., Bair, Thomas B., Glover, Rebecca B., Cohen, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326648/
https://ncbi.nlm.nih.gov/pubmed/22383394
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