Synthesis of fluorinated maltose derivatives for monitoring protein interaction by (19)F NMR

A novel reporter system, which is applicable to the (19)F NMR investigation of protein interactions, is presented. This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein–ligand or protein–protein interactions of proteins fused or tagged to the maltose-binding protein (MBP...

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Bibliografske podrobnosti
Main Authors: Braitsch, Michaela, Kählig, Hanspeter, Kontaxis, Georg, Fischer, Michael, Kawada, Toshinari, Konrat, Robert, Schmid, Walther
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2012
Teme:
Full Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326624/
https://ncbi.nlm.nih.gov/pubmed/22509216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.51
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