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Organic synthesis using (diacetoxyiodo)benzene (DIB): Unexpected and novel oxidation of 3-oxo-butanamides to 2,2-dihalo-N-phenylacetamides

A novel and reliable method for the direct preparation of 2,2-dihalo-N-phenylacetamides is reported. The key transformation involves the cleavage of a carbon–carbon bond in the presence of DIB and a Lewis acid as the halogen source, and thus this method significantly expands the value of DIB as a un...

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Detalhes bibliográficos
Main Authors: Liu, Wei-Bing, Chen, Cui, Zhang, Qing, Zhu, Zhi-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326611/
https://ncbi.nlm.nih.gov/pubmed/22509203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.38
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