Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases

INTRODUCTION: Activation status of the phosphatidylinositol 3-kinase (PI3K) pathway in breast cancer brain metastases (BCBMs) is largely unknown. We examined expression of phospho(p)-AKT, p-S6, and phosphatase and tensin homologue (PTEN) in BCBMs and their implications for overall survival (OS) and...

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Hlavní autoři: Adamo, Barbara, Deal, Allison M, Burrows, Emily, Geradts, Joseph, Hamilton, Erika, Blackwell, Kimberly L, Livasy, Chad, Fritchie, Karen, Prat, Aleix, Harrell, J Chuck, Ewend, Matthew G, Carey, Lisa A, Miller, C Ryan, Anders, Carey K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326567/
https://ncbi.nlm.nih.gov/pubmed/22132754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3071
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