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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion

INTRODUCTION: Inflammatory breast cancer (IBC) is an aggressive, metastatic and highly angiogenic form of locally advanced breast cancer with a relatively poor three-year survival rate. Breast cancer invasion has been linked to proteolytic activity at the tumor cell surface. Here we explored a role...

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Detalhes bibliográficos
Main Authors: Victor, Bernadette C, Anbalagan, Arulselvi, Mohamed, Mona M, Sloane, Bonnie F, Cavallo-Medved, Dora
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326557/
https://ncbi.nlm.nih.gov/pubmed/22093547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3058
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