Sugar Nucleotide Recognition by Klebsiella pneumoniae UDP-d-Galactopyranose Mutase: Fluorinated Substrates, Kinetics and Equilibria

A series of selectively fluorinated and other substituted UDP-d-galactose derivatives have been evaluated as substrates for Klebsiella pneumoniae UDP-d-galactopyranose mutase. This enzyme, which catalyses the interconversion of the pyranose and furanose forms of galactose as its UDP adduct, is a pro...

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Bibliographic Details
Main Authors: Errey, James C., Mann, Maretta C., Fairhurst, Shirley A., Hill, Lionel, McNeil, Michael R., Naismith, James H., Percy, Jonathan M., Whitfield, Chris, Field, Robert A.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326532/
https://ncbi.nlm.nih.gov/pubmed/19225684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b815549f
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