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SUMO protease SENP1 induces isómerization of the scissile peptide bond
Small ubiquitin-like modifier (SUMO)-specific protease SENP1 processes SUMO-1, SUMO-2 and SUMO-3 to mature forms and deconjugates them from modified proteins. To establish the proteolytic mechanism, we determined structures of catalytically inactive SENP1 bound to SUMO-1–modified RanGAP1 and to unpr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326531/ https://ncbi.nlm.nih.gov/pubmed/17099698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1172 |
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