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Mutagenesis of pairwise combinations of histone amino-terminal tails reveals functional redundancy in budding yeast

A large body of literature provides compelling evidence for the role of evolutionarily conserved core histone residues in various biological processes. However, site-directed mutagenesis of individual residues that are known to be sites of posttranslational modifications often does not result in cle...

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Autors principals: Kim, Jung-Ae, Hsu, Jer-Yuan, Smith, M. Mitchell, Allis, C. David
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326485/
https://ncbi.nlm.nih.gov/pubmed/22451923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203453109
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