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A Processive Carbohydrate Polymerase That Mediates Bifunctional Catalysis Using a Single Active Site

Even in the absence of a template, glycosyltransferases can catalyze the synthesis of carbohydrate polymers of specific sequence. The paradigm has been that one enzyme catalyzes the formation of one type of glycosidic linkage, yet certain glycosyltransferases generate polysaccharide sequences compos...

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Detalhes bibliográficos
Main Authors: May, John F., Levengood, Matthew R., Splain, Rebecca A., Brown, Christopher D., Kiessling, Laura L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326345/
https://ncbi.nlm.nih.gov/pubmed/22217153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201820p
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