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Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions

The continuous monolayer of intestinal epithelial cells (IECs) lining the gut lumen functions as the site of nutrient absorption and as a physical barrier to prevent the translocation of microbes and associated toxic compounds into the peripheral vasculature [1]. IECs also express host defense prote...

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Autores principales: Shifrin, David A., McConnell, Russell E., Nambiar, Rajalakshmi, Higginbotham, James N., Coffey, Robert J., Tyska, Matthew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326206/
https://ncbi.nlm.nih.gov/pubmed/22386311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.02.022
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