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Visualising molecular juggling within a B(12)-dependent methyltransferase complex

Derivatives of vitamin B(12) are used in methyl group transfer in biological processes as diverse as methionine synthesis in humans and CO(2) fixation in acetogenic bacteria(1–3). This seemingly straightforward reaction requires large, multimodular enzyme complexes that adopt multiple conformations...

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Detalhes bibliográficos
Main Authors: Kung, Yan, Ando, Nozomi, Doukov, Tzanko I., Blasiak, Leah C., Bender, Güneş, Seravalli, Javier, Ragsdale, Stephen W., Drennan, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326194/
https://ncbi.nlm.nih.gov/pubmed/22419154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10916
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