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Polypurine/polypyrimidine hairpins form a triple helix structure at low pH.

1D and 2D NMR investigations of the 15 residue deoxynucleotide sequence d(TCTCTC-TTT-GAGAGA) show that above pH = 6.5 the molecule adopts a B-form hairpin conformation. As the pH is lowered below 6.5 molecules progressively associate in pairs to form a partially triple helical, partially single stra...

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Udgivet i:Nucleic Acids Res
Principais autores: Mooren, M M, Pulleyblank, D E, Wijmenga, S S, Blommers, M J, Hilbers, C W
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1990
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332605/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.22.6523
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