Role of Misfolded N-CoR Mediated Transcriptional Deregulation of Flt3 in Acute Monocytic Leukemia (AML)-M5 Subtype

The nuclear receptor co-repressor (N-CoR) is a key component of the generic multi-protein complex involved in transcriptional control. Flt3, a key regulator of hematopoietic cell growth, is frequently deregulated in AML (acute myeloid leukemia). Here, we report that loss of N-CoR-mediated transcript...

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Detaylı Bibliyografya
Asıl Yazarlar: Nin, Dawn Sijin, Kok, Wai Kay, Li, Feng, Takahashi, Shinichiro, Chng, Wee Joo, Khan, Matiullah
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326026/
https://ncbi.nlm.nih.gov/pubmed/22514634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034501
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