Epcam, CD44, and CD49f Distinguish Sphere-Forming Human Prostate Basal Cells from a Subpopulation with Predominant Tubule Initiation Capability

BACKGROUND: Human prostate basal cells expressing alpha-6 integrin (CD49f(Hi)) and/or CD44 form prostaspheres in vitro. This functional trait is often correlated with stem/progenitor (S/P) activity, including the ability to self-renew and induce differentiated tubules in vivo. Antigenic profiles tha...

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Autores principales: Guo, Changyong, Liu, Haibo, Zhang, Bao-Hui, Cadaneanu, Radu M., Mayle, Aqila M., Garraway, Isla P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326009/
https://ncbi.nlm.nih.gov/pubmed/22514625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034219
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