3,3′-Diindolylmethane Induces G(1) Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells

Certain bioactive food components, including indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) from cruciferous vegetables, have been shown to target cellular pathways regulating carcinogenesis. Previously, our laboratory showed that dietary I3C is an effective transplacental chemopreventive a...

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Bibliographic Details
Main Authors: Shorey, Lyndsey E., Hagman, Amanda M., Williams, David E., Ho, Emily, Dashwood, Roderick H., Benninghoff, Abby D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325915/
https://ncbi.nlm.nih.gov/pubmed/22514694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034975
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