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Infection of cultured striatal neurons with a defective HSV-1 vector: implications for gene therapy.

Several neurological diseases which affect the corpus striatum are candidates for gene therapy. We have developed a defective Herpes Simplex Virus (HSV-1) vector system to introduce genes into postmitotic cells, such as neurons. The prototype vector, pHSVlac, contains a transcription unit which plac...

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Detalles Bibliográficos
Main Authors: Freese, A, Geller, A
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC332584/
https://ncbi.nlm.nih.gov/pubmed/1662813
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