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Structure of AKR1C3 with 3-phenoxybenzoic acid bound
Aldo–keto reductase 1C3 (AKR1C3) is a human enzyme that catalyzes the NADPH-dependent reduction of steroids and prostaglandins. AKR1C3 overexpression is associated with the proliferation of hormone-dependent cancers, most notably breast and prostate cancers. Nonsteroidal anti-inflammatory drugs (NSA...
में बचाया:
मुख्य लेखकों: | , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
International Union of Crystallography
2012
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325808/ https://ncbi.nlm.nih.gov/pubmed/22505408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112009049 |
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