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Structure of AKR1C3 with 3-phenoxybenzoic acid bound

Aldo–keto reductase 1C3 (AKR1C3) is a human enzyme that catalyzes the NADPH-dependent reduction of steroids and prostaglandins. AKR1C3 overexpression is associated with the proliferation of hormone-dependent cancers, most notably breast and prostate cancers. Nonsteroidal anti-inflammatory drugs (NSA...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jackson, Victoria J., Yosaatmadja, Yuliana, Flanagan, Jack U., Squire, Christopher J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: International Union of Crystallography 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325808/
https://ncbi.nlm.nih.gov/pubmed/22505408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112009049
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