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Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance

Mammalian acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoAs to form free fatty acids plus CoA, but their metabolic functions remain undefined. Thioesterase superfamily member 1 (Them1; synonyms Acot11, StarD14, and brown fat inducible thioesterase) is a long-chain fatty acyl-...

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Autori principali: Zhang, Yongzhao, Li, Yingxia, Niepel, Michele W., Kawano, Yuki, Han, Shuxin, Liu, Sihao, Marsili, Alessandro, Larsen, P. Reed, Lee, Chih-Hao, Cohen, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325675/
https://ncbi.nlm.nih.gov/pubmed/22427358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116011109
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